Sea Cucumber Research
ACTIVE INGREDIENTS OF SEA CUCUMBER
Acetylated Triterpene Glycosides and Their Biological Activity from Holothuroidea Reported in the Past Six Decades
Marine Drugs 2016.
High-Value Components and Bioactives from Sea Cucumbers for Functional Foods - A Review
Marine Drugs 2011.
Medicinal and health benefit effects of functional sea cucumbers
Journal of Traditional and Complementary Medicine 2018.
Pharmacological Potential of Sea Cucumbers
International Journal of Molecular Science 2018.
IMMUNOLOGICAL HEALTH EFFECT
Dietary enhances the respiratory and intestinal mucosal immunity in immunosuppressive mice.
Bioscience, Biotechnology, and Biochemistry 2014.
Effects of sulfated fucan from the sea cucumber Stichopus japonicus on natural killer cell activation and cytotoxicity
International Journal of Biological Macromolecules 2018.
Immunomodulatory effect of Stichopus japonicus acid mucopolysaccharide on experimental hepatocellular carcinoma in rats.
Molecules 2013.
Immunomodulatory Properties of Frondoside A, a Major Triterpene Glycoside from the North Atlantic Commercially Harvested Sea Cucumber Cucumaria frondosa
Journal of Medicinal Food 2008.
Structure of cucumarioside I2 from the sea cucumber Eupentacta fraudatrix (Djakonov et Baranova) and cytotoxic and immunostimulatory activities of this saponin and relative compounds
Natural Product Research 2013.
ANTI-MICROBIAL & ANTI-VIRAL
Antibacterial, antifungal and cytotoxic effects of a sea cucumber Holothuria leucospilota, from the north coast of the Persian Gulf
Journal of the Marine Biological Association of the United Kingdom 2013.
Fucosylated Chondroitin Sulfate Inhibits Plasmodium falciparum Cytoadhesion and Merozoite Invasion
Antimicrob Agents Chemother 2014.
Hemolytic C-Type Lectin CEL-III from Sea Cucumber Expressed in Transgenic Mosquitoes Impairs Malaria Parasite Development
PLOS Pathogen 2007.
The effect of eating sea cucumber jelly on Candida load in the oral cavity of elderly individuals in a nursing home.
Marine Drugs 2013.
ANTI-INFLAMMATORY
Anti-proliferative and anti-inflammatory activities of the sea cucumber aqueous extract
SAGE Open Med 2018.
Evaluation of cytotoxicity and anti-inflammatory effects of saponin isolated from Holothuria leucospilota Sea cucumber
Journal of Cellular Immunotherapy 2015.
Sea cucumber (Isostichopus badionotus) body-wall preparations exert anti-inflammatory activity in vivo
PharmaNutrition 2018.
Structural comparison, antioxidant and anti-inflammatory properties of fucosylated chondroitin sulfate of three edible sea cucumbers
Carbohydrate Polymers 2018.
ANTI-FATIGUE
Anti-fatigue Effect of Sea Cucumber Stichopus japonicus in
Mice
Food science 2010.
The potency of sandfish (holothuria scraba) as a source of natural aphrodisiacs.
World Academy of Science 2013.
ANIT-CANCER
Isolation of sphingoid bases of sea cucumber cerebrosides
and their cytotoxicity against human colon cancer cells.
Bioscience, Biotechnology & Biochemistry 2006.
Triterpene Glycosides from Sea Cucumber Holothuria scabra with Cytotoxic Activity
Chinese Herbal Medicines 2012.
PE, a new sulfated saponin from sea cucumber, exhibits anti-angiogenic and anti-tumor activities in vitro and in vivo.
Cancer biology & therapy 2005.
ANTI-DIABETIC & GLUCOSE LOWERING
Anti-diabetic activity of Holothuria thomasi saponin
Biomedicine & Pharmacotherapy 2016.
Dietary saponins of sea cucumber ameliorate obesity, hepatic steatosis, and glucose intolerance in high-fat-diet-fed mice.
Journal of Medicinal Food 2012.
Eicosapentaenoic acid-enriched phosphatidylcholine isolated from Cucumaria frondosa exhibits anti-hyperglycemic effects via activating phosphoinositide 3-kinase/protein kinase B signal pathway
Journal Biosci Bioeng 2014.
Fucoidan from sea cucumber Cucumaria frondosa exhibits anti-hyperglycemic effects in insulin resistant mice via activating the PI3K/PKB pathway and GLUT4.
Journal of Bioscience & Bioengineering 2016.
Fucosylated Chondroitin Sulfate from Sea Cucumber Improves Insulin Sensitivity via Activation of PI3K/PKB Pathway
Journal of Food Science 2014.
ANTI-HYPERLIPIDEMIC
Antioxidant and antihyperlipidemic activities of polysaccharides from sea cucumber
Carbohydrate Polymers 2012.
Effects of Bioactive Components of Sea Cucumber on the Serum, Liver Lipid Profile and Lipid Absorption
Bioscience, Biotechnology, and Biochemistry 2012.
Hypolipidemic effect of glycosaminoglycans from the sea cucumber Metriatyla scabra in rats fed a cholesterol-supplemented diet.
Journal of Agric Food Chem 2002.
Inhibitory effect of fucosylated chondroitin sulfate from the sea cucumber Acaudina molpadioides on adipogenesis is dependent on Wnt/β-catenin pathway
Journal of Bioscience and Bioengineering 2015.
Nutritional value of Holothuria forskali protein and effects on serum lipid profile in rats.
Journal of Physiol Biochem 2000.
Saponins of sea cucumber attenuate atherosclerosis in ApoE−/− mice via lipid-lowering and anti-inflammatory properties
Journal of Functional Foods 2018.
Sulfation pattern of fucose branches affects the anti- hyperlipidemic activities of fucosylated chondroitin sulfate
Carbohydrate Polymers 2016.
LOWER BLOOD PRESSURE
Angiotensin-I Converting Enzyme (ACE) Inhibitory and Anti-Hypertensive Effect of Protein Hydrolysate from Actinopyga lecanora (Sea Cucumber) in Rats
Marine Drugs 2016.
Angiotensin-I Converting Enzyme (ACE) Inhibitory and Anti-Oxidant Activities of Sea Cucumber (Actinopyga lecanora) Hydrolysates
International Journal of Molecular Science 2015.
Antihypertensive effect and purification of an ACE inhibitory peptide from sea cucumber gelatin hydrolysate
Process Biochemistry 2007.
ANTI-COAGULANT & ANTI-THROMBOTIC
Basic and clinical study on the antithrombotic mechanism of glycosaminoglycan extracted from sea cucumber
Chinese medical journal 2000.
Primary structure and anticoagulant activity of fucoidan from the sea cucumber Holothuria polii
International Journal of Biological Macromolecules 2019.
BRAIN & NERVOUS SYSTEM HEALTH EFFET
Anti-Parkinson activity of bioactive substances extracted from Holothuria leucospilota
Biomedicine & Pharmacotherapy 2019.
Protective effects of cerebrosides from sea cucumber and starfish on the oxidative damage in PC12 cells.
Journal Oleo Science 2013.
JOINT & BONE HEALTH EFFECT
Sea cucumber : a natural arthritis treatment
Dynamic Chiropractic 1996.
GASTROINTESTINAL HEALTH EFFECT
Ameliorative effect of the sea cucumber Holothuria arenicola extract against gastric ulcer in rats
The Journal of Basic & Applied Zoology 2015.
Protective effect of sea cucumber (Acaudina molpadioides) fucoidan against ethanol-induced gastric damage
Food Chemistry 2012.
KIDNEY HEALTH EFFECT
Anti-fatique effect of sea cucumber Stichopus japonicus in mice.
Food science 2010.
The potency of sandfish (holothuria scraba) as a source of natural aphrodisiacs.
World Academy of Science, Engineering and Technology 2013.
Nutritional value of Holothuria forskali protein and effects on serum lipid profile in rats.
Physio. Biochem 2000.
SKIN HEALTH EFFECT
Effect of Low Molecular Weight Oligopeptides Isolated from Sea Cucumber on Diabetic Wound Healing in db/db Mice
Marine Drugs 2018.
Skin whitening and anti-corrugation activities of glycoprotein fractions from liquid extracts of boiled sea cucumber
Asian Pacific Journal of Tropical Medicine 2016.
Wound healing activity of total sulfated glycosaminoglycan (GAG) from Stichopus vastus and Stichopus hermanni integumental tissue in rats.
International Journal of Molecular Science 2010 .
METABOLIC HEALTH EFFECT